Manna Calmer Adult 3 Month Special

Calmer is a calmative of natural origin derived from Sceletium tortuosum, traditionally used to manage stress, tension and anxiety.

Not recommended for children under the age of 15 years

Contra-Indications

Hypersensitivity to any of the ingredients

Warning and Special Precautions

Concurrent use with any psychiatric medication, including mood stabilisers, antidepressants and anti-anxiety medication should be discussed with a registered healthcare professional. Not to be taken in conjunction with Monoamine oxidase inhibitors (MAOI’s).

Safety during pregnancy and lactation has not been established. Do not use during pregnancy.

Interactions

No known drug interactions have been documented.

Side-Effects and Special Precautions

In rare cases transient mild headache, abdominal discomfort or nausea may occur. Should any adverse reactions occur, discontinue use immediately

Known Symptoms of Overdosage and Particulars of its Treatment

These may include extreme euphoria, dizziness, tinnitus, sweating, nausea, vomiting, diarrhoea, anxiety and mental confusion followed by sedation.

Over-dosage or prolonged use should not give rise to any toxic effects. However, should any severe symptoms occur following overdosage, consult your doctor or nearest hospital immediately Treatment is supportive and symptomatic.

1. Acute Effects of Sceletium tortuosum (Zembrin), a Dual 5-HT Reuptake and PDE4 Inhibitor, in the Human Amygdala and its Connection to the Hypothalamus – 2013 Dec; 38(13): 2708–2716
2. The potential health benefits of taurine in cardiovascular disease – Exp Clin Cardiol. 2008 Summer; 13(2): 57–65
3. The blood-brain barrier in brain homeostasis and neurological diseases – Biochimica et Biophysica Acta (BBA) – Biomembranes Volume 1788, Issue 4, April 2009, Pages 842–857